Comparative genomics and receptor signaling in MBL and CLL arising in siblings

Comparative genomics and receptor signaling in MBL and CLL arising in siblings - MBL - CLL

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41246

Enrollment

232

Registered

2013-01-31

Start date

2015-02-16

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Monoclonal B-cell lymphocytosis white blood cells without clinical relevance

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: diagnosis of CLL or a sibling with CLL

Exclusion criteria

Exclusion criteria: n.a.

Design outcomes

Primary

Measure	Time frame
1) Definition of genetic differences between MBL en CLL as detected by whole exome sequencing and SNP microarray analysis 2) Detection of antigen-independent BCR signaling in MBL en CLL.	—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results