Er wordt geen aandoening bestudeerd. n.v.t.
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Caucasian, right handed, normal (or corrected to normal) vision, healthy, BMI 18-25 kg/m2, normal sense of taste and smell, non-smoking, fMRI compatible, no history of neurological or psychiatric disorders, Male, Age range: 18-30, fluent in dutch.
Exclusion criteria
Exclusion criteria: MR incompatable (posibility of any incompatible metal objects inside the body), History of psychiatric disorders, History of taste-related disorders, Allergies against ingredients of the stimuli, Smokers. Wearing glasses (lenses are allowed) Alcohol/drug abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are: the flavors administered to the subjects (two flavors, one pleasant one unpleasant, plus one neutral), flavor intensities (five concentrations, plus one neutral), the perceived pleasantness and intensity of each flavor solution, the brain activity corresponding to each flavor intensity and pleasantness during administration. In addition the brain activity corresponding to exposure to each IAPS image as well as the ratings of reward and disgust at exposure to these images is used. The outcome of the study (endpoints) will consist of: - The neural activity patterns associated with flavor intensity and valence; - A comparison of the reward and disgust networks found in response to flavors and images. | — |
Countries
Netherlands
Outcome results
None listed