Sensory hyperreactivity
Conditions
Interventions
None listed
Sponsors
Orbis Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Mentally competent; 18 years and older; Chronic cough; Normal long function (FEV1, VC and ratio > 80% of predicted values); Negative histamine provocation test (max fall FEV1 off 10%); Non smokers; No other pulmonary diseases.
Exclusion criteria
Exclusion criteria: Not mentally competent; No cough; Other pulmonary diseases; Post nasal drip; Gastro-oesofageal reflux; Deviation on x-ray; No normal values in long function; Lung infection in the past eight weeks; Use of ACE-inhibitor; Excessive mucus production; Pregnancy or pregnancy wish; Breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All data will be recorded in the pulmonary function laboratory of the Orbis Medical Center in Sittard. The variables that are collected during this studyare divided in the dependent and independent variables. The dependent variables are the number of coughs en the deposit score for chest pain, haorseness, irritation of the throat, runny nose, mucus and irritation of the eyes. The independent variables are concentration inhaled capsaicin, gender and age. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inapplicable | — |
Countries
Netherlands
Outcome results
None listed