atopic Dermatitis Atopic eczema
Conditions
Interventions
Patients are instructed to apply Dermalex eczema cream, a standard emollient or
a dermatocorticosetroid on one side of the body on atopic dermatitis lesions at
least twice a day. The opposite side w
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Clinically diagnosed atopic dermatitis;- Mild to moderate atopic dermatitis, according to total SCORAD score (score
Exclusion criteria
Exclusion criteria: Extensive UV exposure in the last 14 days before study and/or expected during the study. ;- Other skin disease other than AD.;- Use of antibiotics prior to (4 weeks) the study and/or expected use during the study.;- Use of systemic suppressing drugs (e.g. prednisone, methothrexate) prior to (4 weeks) the study and/or expected use during the study;-Severe disorders within the last 6 months before study (e.g. cancer, acute cardiac or circularity disorders, HIV, infectious hepatitis);- Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration in days of used ointments until AD symptoms have improved, defined as a decrease in SCORAD-score of 5 points | — |
Secondary
| Measure | Time frame |
|---|---|
| - The amount of used cream/ointments (per day and total) - Change in cytokine levels, lipid profile, Trans epidermal water loss, erythema and PH after the different treatments. - presence of mutations on the Fillagrin-gene | — |
Countries
Netherlands
Outcome results
None listed