The effect of Spherical Nucleic Acids on target gene expression in full thickness biopsies taken from lesional skin of volunteers with psoriasis vulgaris.

The effect of Spherical Nucleic Acids on target gene expression in full thickness biopsies taken from lesional skin of volunteers with psoriasis vulgaris. - The effect of SNA on psoriasis skin gene expression.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41100

Enrollment

Registered

2014-12-03

Start date

2014-12-17

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with psoriasis vulgaris, moderate to sever.

Exclusion criteria

Exclusion criteria: -Volunteers undergoing light therapy or taking systemic drugs such as methotrexate or cyclosporine A. -Volunteers using local topical corticosteroids. -Volunteers who develop psoriasis at wound sites (Köbner phenomenon). -Volunteers with atopic dermatitis/eczematous skin conditions. -Pregnancy

Design outcomes

Primary

Measure	Time frame
A decrease in skin mediator RNA levels.	—

Countries

Netherlands

Outcome results