Heterogeneity of Activation Recovery Interval and Restitution in Non-Ischemic Cardiomyopathy and its relation to Ventricular Arrhythmias

Heterogeneity of Activation Recovery Interval and Restitution in Non-Ischemic Cardiomyopathy and its relation to Ventricular Arrhythmias - ARI/Restitution

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41046

Enrollment

Registered

2015-03-02

Start date

2014-10-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Life-threatening arrhythmias Ventricular Arrhythmias

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Cases: This population will consist of consecutive NICM patients with previous documentation of ventricular arrhythmias (sustained monomorphic VT, polymorphic VT or ventricular fibrillation) scheduled for epicardial or endocardial electrophysiological study with or without ventricular tachycardia ablation. Controls: This group will consist of consecutive patients without structural heart disease referred for mapping and ablation of idiopathic Premature Ventricular Contractions.

Exclusion criteria

Exclusion criteria: All subjects: Age

Design outcomes

Primary

Measure	Time frame
Electroanatomical mapping data: ARI and APDR values (derived from unipolar signals) from predefined sites Inducibility and type of VA during electrophysiology study Inducibility and type of VA during ARI/APDR pacing protocol Occurrence and type of spontaneous VA during 24 month follow-up	—

Secondary

Measure	Time frame
Mortality (all cause, cardiac, arrhythmic)	—

Countries

Netherlands

Outcome results