normale fysiologie van het Maagdarmstelsel fysiologie of gastric emptying
Conditions
Interventions
Stimuli:
Shake B
Low viscosity - High nutrient
Shake D
High viscosity - High nutrient
Shake A
Low viscosity - Low nutrient
Shake C
High viscosity - Low nutrient
Control
Water
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Male 18-35 BMI: 18.5 - 25.0 kg/m2 Healthy as judged by the participant
Exclusion criteria
Exclusion criteria: • Failing to meet one or more of the inclusion criteria • Having difficulties with swallowing/eating • Weight loss or weight gain of 5 kg or more during the last two months • Having an endocrine or gastrointestinal disorder which may affect gastric emptying. • Being allergic/intolerant for products under study (see form F1) • Working at the Division of Human Nutrition (WUR) • Current participation in other research from the Division of Human Nutrition (WUR)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is stomach size/content as measured by MRI over a time of 2 hours. The outcome of the study is the difference in these measured parameters between the 4 treatments. | — |
Secondary
| Measure | Time frame |
|---|---|
| Participants will be asked to rate their feelings of appetite on a questionnaire just before and after they are scanned. This questionnaire will consist of four dimensions of appetite, i.e. hunger, fullness, desire to eat and prospective consumption. Moreover, participants will rate their thirst, and wellbeing i n this questionnaire. In addition, palatability and desire to consume the stimuli will be rated in the scanner. Responses will be reported on 100-mm visual analogue scales. Exhaled air is measured for for isotopic enrichment using mass spectrometry, in order to compare this with the MRI data. | — |
Countries
Netherlands
Outcome results
None listed