Effects of local oestrogen on vaginal microcirculation in the treatment of vaginal atrophy

Effects of local oestrogen on vaginal microcirculation in the treatment of vaginal atrophy - VAMP-3 study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON41036

Enrollment

Registered

2014-09-16

Start date

2014-10-13

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal atrophy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Women with vaginal atrophy diagnosed based on: a. The presence of one or more of the following symptoms: - Vaginal dryness - Vaginal itching/irritation - Dyspareunia b. The presence of one or more of the following symptoms on physical examination: - Presence of vaginal wall pallor and petechiae - Friability of the vaginal wall (defined as any bleeding occurring during examination) - Conization (markedly decreased elasticity) - Absence of rugae

Exclusion criteria

Exclusion criteria: 1. Previous pelvic surgery 2. Cardiovascular disease (e.g. angina pectoris, hypertension) 3. Inflammatory disease (e.g. rheumatoid arthritis, eczema) 4. Other systemic illness (e.g. (non-) insulin dependent diabetes mellitus) 5. Medications (e.g. anticoagulants, anti-inflammatory, or immunosuppressive agents) that could influence the microcirculation

Design outcomes

Primary

Measure	Time frame
Differences in measurements of microcirculatory parameters in patients with VA and before and after treatment with local oestrogen.	—

Countries

Netherlands

Outcome results