Less rumination, less paranoid thinking? The effects of reducing rumination/worry in patients with persecutory delusions: a pilot study

Less rumination, less paranoid thinking? The effects of reducing rumination/worry in patients with persecutory delusions: a pilot study - Less rumination, less paranoid thinking?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON41032

Enrollment

Registered

2014-09-22

Start date

2014-06-20

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paranoia Persecutory delusions

Interventions

COMET is a cognitive treatment for rumination in depressed patients, developed by Ekkers and collegues (2011). The COMET protocol encompasses six steps or stages: (1) Motivation enhancing, (2) treat

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age above 18, primary diagnosis of schizophrenia, schizoaffective disorder, or delusional disorder, all with current experience of persecutory delusions or paranoid thinking based on the criteria from the Diagnostic and Statistical Manual of Mental Disorders IV. Text Revision (DSM-IV-TR) and verified with the Mini International Neuropsychiatric Interview Plus (MINI-plus), a score above 50 on the persecutory item from the Green Paranoid Thought Scales (GPTS) and one question from the Positive and Negative Syndrome Scale (PANSS) regarding delusion which has to have a score between four and eight.

Exclusion criteria

Exclusion criteria: Insufficient knowledge of the Dutch language, cognitive impairment with a cut-off score of

Design outcomes

Primary

Measure	Time frame
Primary measurements will be the scales taken from the Green Paranoid Thought Scale (GPTS) that assesses delusion, and the Psychotic Symptoms Rating Scale - Delusions (PSYRATS-DRS), rumination, assessed with the Ruminative Response Scale (RRS) and worry, assessed with the Penn State Worry Questionnaire (PSWQ).	—

Secondary

Measure	Time frame
Secondary measurements will be anxiety, assessed with the Beck Anxiety Inventory (BAI) and depression, assessed with the Beck Inventory of Depression - II (BDI2). In addition feasibility will be evaluated by interviewing patients on their opinion about the treatment and its effects. Also the participating therapists will be interviewed on their opinion about the feasibility and effectiveness of the treatment and on their collaboration. If a patient drops out of treatment, the reason for drop-out will be assessed by contacting the patient and the therapist.	—

Measure

Time frame

Secondary measurements will be anxiety, assessed with the Beck Anxiety Inventory (BAI) and depression, assessed with the Beck Inventory of Depression - II (BDI2). In addition feasibility will be evaluated by interviewing patients on their opinion about the treatment and its effects. Also the participating therapists will be interviewed on their opinion about the feasibility and effectiveness of the treatment and on their collaboration. If a patient drops out of treatment, the reason for drop-out will be assessed by contacting the patient and the therapist.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)