Developmental disorders
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: - member of one of the existing cohorts in which prenatal exposure to environmental chemicals have been measured - written informed consent from the child and both parents
Exclusion criteria
Exclusion criteria: No exclusioncriteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - serum levels of thyroid hormone parameters; - neuropsychological development; - pubertal development (stage of breast-, genital-, pubic hair- and axillar hair development; testicular volume; age at menarche/first ejaculation; serum levels of sex hormones); - physical examination: height, weight, waist circumference and body fat percentage; - serum levels of parameters of energy metabolism (fasting glucose, insulin, HbA1C, leptin, adiponectin, triglycerides, total cholesterol, HDL- and LDL-cholesterol). | — |
Secondary
| Measure | Time frame |
|---|---|
| - serum levels of PCBs, OH-PCBs and PBDEs; - urine levels of BPA, phthalates and PFCs. | — |
Countries
Netherlands
Outcome results
None listed