Veroudering aging senescence
Conditions
Interventions
One session of non-invasive MP with the right wrist flexors and extensors for
35 minutes. The MP+SES group receives SES at 10 Hz trains of 5 pulses of 1ms
during the practice, the MP group only perf
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 18-30 or >65, female or male gender, right-handed
Exclusion criteria
Exclusion criteria: Fracture in the upper extremity over the past year, neurological disorders, pregnancy, medicine known to affect nerve conduction, a history of epilepsy, use of a pacemaker, and metal in the brain/skull
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the reduction in absolute error during MP in the trained right hand. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanistic measures include the corticospinal excitability indexed by the size of the motor evoked potentials (MEPs) produced by transcranial magnetic stimulation (TMS), short-interval intracortical inhibition (SICI), and intracortical facilitation (ICF). | — |
Countries
Netherlands
Outcome results
None listed