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MYOcardial ischemia detection by circulating bioMARKERs: * the MYOMARKER-study*

MYOcardial ischemia detection by circulating bioMARKERs: * the MYOMARKER-study* - MYOMARKER

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON40975
Enrollment
1265
Registered
2014-06-26
Start date
2014-08-12
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

angina (pectoris) ischemic coronary artery disease

Interventions

None listed

Sponsors

Meander Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients (age >18yr), who are being evaluated in the Meander Medical Center cardiology outpatient clinic with symptoms suggestive for ischemic coronary artery disease, and who will undergo radionuclide myocardial perfusion imaging (rMPI) as indicated by their own cardiologist.

Exclusion criteria

Exclusion criteria: - Age

Design outcomes

Primary

MeasureTime frame
Parameter; Extracellular vesicle protein- and miRNA-concentration, and gene expression profiles in circulating cells. Endpoint: Objectified ischemic coronary artery disease, determined by radionuclide myocardial perfusion imaging (Rubidium-82).

Secondary

MeasureTime frame
Follow-up: all-cause mortality, cardiovascular death, non-fatal MI, coronary revascularisation, stroke, and peripheral vascular interventions.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)