Discovery of biomarkers for cervical neoplasia by genome-wide gene-expression profiling

Discovery of biomarkers for cervical neoplasia by genome-wide gene-expression profiling - Gene expression profiling in cervical neoplasia

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40971

Enrollment

165

Registered

2015-02-24

Start date

2015-05-26

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(premaligant lesions) of cervical cancer cervical neoplasia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All groups: Age>=18 years Group 1. undergoing surgery with removal of the cervix for benign abnormalities. Group 2. undergoing loop electrosurgical excision procedure during colposcopy for (suspected) cervical intraepithelial neoplasia lesion Group 3. undergoing anesthetized physical examination or surgery in case of (suspected) cervical cancer

Exclusion criteria

Exclusion criteria: Pregnant during the tissue sampling or pregnancy in the last 3 months

Design outcomes

Primary

Measure	Time frame
The main study parameter is the genome-wide expression profile of the different samples collected in this study, pooled by groups of CIN lesions, cervical cancer and normal cervical tissue.	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results