CARDIAC EFFECTS OF HIGH THORACIC EPIDURAL ANAESTHESIA DURING BICYCLE EXERCISE: AN ECHOCARDIOGRAPHIC STUDY

CARDIAC EFFECTS OF HIGH THORACIC EPIDURAL ANAESTHESIA DURING BICYCLE EXERCISE: AN ECHOCARDIOGRAPHIC STUDY - cardiac effects of HTEA during bicycle exercise

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40956

Enrollment

Registered

2014-06-02

Start date

2015-01-13

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

invloed van sympathicusblokkade door HTEA op de functie van het hart tijdens inspanning cardiac function epidural anesthesia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients younger than 65 years ASA 1 or 2 patients undergoing thoracic surgery under thoracic epidural anaesthesia

Exclusion criteria

Exclusion criteria: Contra-indications for thoracic epidural: * Infection of the skin in the area of the epidural site * A history of neurological diseases * A history of bleeding diathesis * Muscle diseases * Hypersensitive to local anesthetics History of Coronary Artery disease (CAD) Known decreased ejection

Design outcomes

Primary

Measure	Time frame
the first primary objective is the expected change in pulsed tissue Doppler systolic velocities of the mitral annulus (MV S*) during maximal exercise.	—

Secondary

Measure	Time frame
CO: Cardiac output HR: Heart rate SBP DBP MAP MV A: Peak mitral inflow velocity during atrial contraction phase MV A: Mitral annular diastolic velocity during atrial contraction MV E: Peak mitral inflow velocity during early filling phase MV E: Mitral annular diastolic velocity during early filling MV E/A: Ratio of E to A MV E DT: Time interval required for the E velocity to decline from its peak to the baseline MV S: Mitral annular systolic velocity TV A: Peak tricuspid inflow velocity during atrial contraction phase TV A: Tricuspid annular diastolic velocity during atrial contraction TV E: Peaktricuspid inflow velocity during early filling phase TV E: Tricuspid annular diastolic velocity during early filling TV E/A: Ratio of tricuspid E to A TV S: Tricuspid annular systolic velocity	—

Measure

Time frame

CO: Cardiac output HR: Heart rate SBP DBP MAP MV A: Peak mitral inflow velocity during atrial contraction phase MV A*: Mitral annular diastolic velocity during atrial contraction MV E: Peak mitral inflow velocity during early filling phase MV E*: Mitral annular diastolic velocity during early filling MV E/A: Ratio of E to A MV E DT: Time interval required for the E velocity to decline from its peak to the baseline MV S*: Mitral annular systolic velocity TV A: Peak tricuspid inflow velocity during atrial contraction phase TV A*: Tricuspid annular diastolic velocity during atrial contraction TV E: Peaktricuspid inflow velocity during early filling phase TV E*: Tricuspid annular diastolic velocity during early filling TV E/A: Ratio of tricuspid E to A TV S*: Tricuspid annular systolic velocity

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Countries

Netherlands

Outcome results