Late LTP-like plasticity effects of tDCS in subacute stroke patients

Late LTP-like plasticity effects of tDCS in subacute stroke patients - tDCS-LPSS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40946

Enrollment

Registered

2014-12-05

Start date

2014-11-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular accident Stroke

Interventions

Patients who are enrolled in this study will receive standard care with the addition of two one hour tDCS sessions (sham or real stimulation) per week for 4 weeks.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Subacute stroke (within 1-3 weeks post stroke) • Acute hemiparesis with single thromboembolic non-hemorrhagic infarction documented by a neurologist • Aged 18-79

Exclusion criteria

Exclusion criteria: • Absence of recordable MEPs from the ADM after TMS • Absence of voluntary movement (MRC

Design outcomes

Primary

Measure	Time frame
To investigate whether late LTP-like plasticity tDCS increases the effectiveness of upper limb rehabilitation therapy after stroke.	—

Secondary

Measure	Time frame
• To investigate whether the application of tDCS in subacute stroke patients increases quality of life, cognitive performance and depression. • To investigate whether late LTP-like plasticity tDCS increases the effectiveness of lower limb rehabilitation therapy after stroke. • To investigate the safety, side effects and drop-out rates for tDCS as an integral part of upper limb rehabilitation in the first months post stroke.	—

Measure

Time frame

• To investigate whether the application of tDCS in subacute stroke patients increases quality of life, cognitive performance and depression. • To investigate whether late LTP-like plasticity tDCS increases the effectiveness of lower limb rehabilitation therapy after stroke. • To investigate the safety, side effects and drop-out rates for tDCS as an integral part of upper limb rehabilitation in the first months post stroke.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)