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Determining the efficacy of chordotomy using laser evoked potentials: a pilot study

Determining the efficacy of chordotomy using laser evoked potentials: a pilot study - Chordo study

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON40920
Enrollment
5
Registered
2015-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic intractable unilateral pain

Interventions

Laser stimulation session Cutaneous heat stimuli are delivered by a 980-nm diode laser (Biolitec, Ceram Optec, Bonn, Germany) to the blackened dorsum of the right and left hand (C6 dermatome). Black
Korenromp et al, 2012]. Recording and Processing Electroencephalography (EEG) recordings will be made to measure brain activity following laser stimulation. EEG epochs recorded 200 msec before and 8

Sponsors

Sint Antonius Ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Unilateral intractable pain • Eligible for Percutaneous Cervical Chordotomy • Informed consent • >18 years

Exclusion criteria

Exclusion criteria: • Recent invasive neurolytic treatment • Dermal lesions at the site of stimulation (i.e. psoriasis, ulcera, infection) • Subject currently has an active implantable device including ICD/pacemaker

Design outcomes

Primary

MeasureTime frame
Laser Evoked Potentials before PCC: N2P2 amplitude, N2 and P2 latency Laser Evoked Potentials after PCC: N2P2 amplitude, N2 and P2 latency—

Secondary

MeasureTime frame
Opioid consumption before PCC (mg/day) calculated in morphine equivalents Opioid consumption after PCC (mg/day) calculated in morphine equivalents—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)