Evaluation of the role of trained innate immunity in the development of rheumatoid arthritis

Evaluation of the role of trained innate immunity in the development of rheumatoid arthritis - Evaluation trained immunity in the development of RA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40866

Enrollment

Registered

2014-07-23

Start date

2014-11-03

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

artralgia reumatoid artritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients with clinically suspect arthralgia and inflammation on the MRI patients diagnosed with RA healthy volunteers aged >=18 years all subjects have to give their written informed consent.

Exclusion criteria

Exclusion criteria: not fulfilling inclusioncriteria

Design outcomes

Primary

Measure	Time frame
In case prolonged increased responsiveness of monocytes is one of the hits in the multiple hit process of RA we anticipate that: - There are differences in monocytes of RA patients and healthy controls. - It is an early phenomenon, so it is already present in patients with clinically suspect arthralgia with subclinical inflammation on the MRI. These hypotheses will be tested in this study.	—

Countries

Netherlands

Outcome results