Effects of coal tar treatment on natural moisturizing factors in atopic dermatitis patients

Effects of coal tar treatment on natural moisturizing factors in atopic dermatitis patients - COAL

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40845

Enrollment

Registered

2014-07-23

Start date

2014-09-22

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dermatitis eczema

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Clinically diagnosed atopic dermatitis - Mild to moderate atopic dermatitis, according to total SCORAD score (objective score

Exclusion criteria

Exclusion criteria: - Extensive UV exposure in the last 14 days before study and/or expected during the study. - Other skin disease other than AD. - Use of antibiotics prior to (4 weeks) the study and/or expected use during the study. - Use of systemic suppressing drugs (e.g. prednisone, methothrexate) prior to (4 weeks) the study and/or expected use during the study -Severe disorders within the last 6 months before study (e.g. cancer, acute cardiac or circularity disorders, HIV, infectious hepatitis) -pregnancy or breastfeeding - Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements.

Design outcomes

Primary

Measure	Time frame
changes in NMF, lipid levels, TEWL, SCORAD-score and cytokine levels	—

Secondary

Measure	Time frame
Presence of filaggrine mutation	—

Countries

Netherlands

Outcome results