The value of ultrasound compared to magnetic resonance imaging in haemophilic arthropathy

The value of ultrasound compared to magnetic resonance imaging in haemophilic arthropathy - US versus MRI in haemophilic arthropathy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40804

Enrollment

Registered

2014-08-14

Start date

2014-11-26

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemophilic arthropathy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Clinical and radiological absent or minimal arthropathy • Participation in MRI study by Den Uijl: - MRI assessment of both knees and ankles by the standardized MRI protocol described by Den Uijl in 2009/2010 - Severe (

Exclusion criteria

Exclusion criteria: • History of inhibitors • Contra indication for MRI • Exclusion of joints in case of a severe joint injury, joint surgery, or development of a target joint since initial MRI assessment in 2009/2010

Design outcomes

Primary

Measure	Time frame
Research question 1: Ultrasound and MRI scores for synovial hypertrophy according to the HEAD-US score and the additive IPSG MRI score respectively.	—

Secondary

Measure	Time frame
Research question 2a: MRI scores for synovial hypertrophy, haemosiderin, and osteochondral defects on the initial MRI, and MRI scores for osteochondral defects at re-examination. Research question 2b: MRI scores for synovial hypertrophy at the initial MRI, and MRI scores for synovial hypertrophy at re-examination. Determinants of interest are: Number of joint bleeds between MRI examinations specified per joint, age, history of joint injuries, and Body Mass Index (BMI).	—

Measure

Time frame

Research question 2a: MRI scores for synovial hypertrophy, haemosiderin, and osteochondral defects on the initial MRI, and MRI scores for osteochondral defects at re-examination. Research question 2b: MRI scores for synovial hypertrophy at the initial MRI, and MRI scores for synovial hypertrophy at re-examination. Determinants of interest are: Number of joint bleeds between MRI examinations specified per joint, age, history of joint injuries, and Body Mass Index (BMI).

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Countries

Netherlands

Outcome results