Identifying protein profile differences between laryngeal cancer of young and elderly patients: a pilot study.

Identifying protein profile differences between laryngeal cancer of young and elderly patients: a pilot study. - H&C-PEP

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40763

Enrollment

Registered

2014-11-19

Start date

2014-12-04

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer of the voice box laryngeal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Newly diagnosed squamous cell laryngeal cancer; Malignancy limited to one side of the larynx; Age =75 years (n=10); Written informed consent; WHO performance status 0-2.

Exclusion criteria

Exclusion criteria: Age >= 65 years and

Design outcomes

Primary

Measure	Time frame
Identification of protein profile differences between laryngeal cancers of young and elderly patients, by comparing differential expression of proteins in cancer and healthy tissue of the same patients, determined by Liquid Chromatography Tandem Mass Spectometry (LC-MS/MS) using the Orbitrap/qTOF mass analyzer.	—

Secondary

Measure	Time frame
Identification of differences between protein interaction network in cancer and healthy tissue between elderly and young laryngeal cancer patients, determined by Liquid Chromatography Tandem Mass Spectometry (LC-MS/MS) using the Orbitrap/qTOF mass analyzer.	—

Countries

Netherlands

Outcome results