depressive disorder depressive symptoms
Conditions
Interventions
Intervention:
E-prescription to an online self-management program (1-2 sessions per week
spread over 5-10 weeks), blended with a few telephonic or face-to-face contacts
with the GP or POH-GGZ.
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: Adult patients, i.e. aged 18 or over; Patients presenting to the GP with a depressive disorder or depressive symptoms; Patients for whom GP considers prescribing an antidepressant.
Exclusion criteria
Exclusion criteria: Patients will excluded if they: - are unwilling to accept randomization to either a psychological (e-prescription) or care as usual. - have an anxiety disorder or obsessive compulsive disorder as primary diagnosis - have current substance abuse (alcohol, drugs) - receive currently treatment for depression (i.e. medication or e-mental health intervention) - have an insufficient command of the Dutch language - have not given an informed consent - No internet available or grossly insufficient computer skills
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are the reduction on depressive symptoms using the HRSD-17 at 12 months, percentage response (50% reduction in symptoms on HRSD-17), remission (HRSD-17 score below 7) at three and twelve months of follow-up, antidepressant use, effect on general health status, functional impairment, treatment satisfaction and cost-effectiveness. | — |
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints: Main endpoint is the reduction in depressive symptoms as assessed by the Hamilton Depression Rating Scale-17 (HRSD-17) from baseline to three months after intervention. | — |
Countries
Netherlands
Outcome results
None listed