Bleeding platelet aggregation disorder
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Women between 18 and 50 years old, with no known disease or drug use.
Exclusion criteria
Exclusion criteria: Current disease, personal and family history of bleeding or coagulation abnormalities, intensive exercise in the three days prior to participation, drug use, use of acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs) in the two weeks prior to participation, usage of the supplement creatine (or a creatine analogue), current smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADP induced platelet aggregation (area under curve and final aggregation) with different concentrations of creatine kinase added in vitro. | — |
Secondary
| Measure | Time frame |
|---|---|
| Endogenous plasma CK activity levels. | — |
Countries
Netherlands
Outcome results
None listed