The feasibility, reliability and validity of the MOX-accelerometer in measuring daily physical endurance in children with a mitochondrial disorder

The feasibility, reliability and validity of the MOX-accelerometer in measuring daily physical endurance in children with a mitochondrial disorder - The MOX-accelerometer in children with a mitochondrial disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40669

Enrollment

Registered

2015-02-10

Start date

2015-02-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mitochondrial encephalomyopathy mitopathy

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Patients: - aged 4-18 years - decreased ATP production in fresh muscle (to same extend as descrease in pyruvateoxidation rate) or mutation in gene known to cause mitochondrial disease - follow-up in NCMD;Heatlhy controls - Healthy - Regular education - Aged 4-18 years

Exclusion criteria

Exclusion criteria: Patients: - Fever - Epilepsia continua - Altered state of conciousness compared to normal;Healthy controls: - Regularly seen by a paediatrician - Complaints of exercise intolerance, muscle complaints or fatigue, more than peers - Official ADHD diagnosis - Sibling with neuromuscular or metabolic disease

Design outcomes

Primary

Measure	Time frame
The feasibility (% of patients), reliability (test-retest, % of data) and validity (correlation with video of standardized movements, correlation with reported activities) of the MOX-accelerometer in children with a mitochondrial disease	—

Countries

Netherlands

Outcome results