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Neurobiological underpinnings of cognitive emotion regulation in younger and older adults

Neurobiological underpinnings of cognitive emotion regulation in younger and older adults - A fMRI study of cognitive emotion regulation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON40649
Enrollment
120
Registered
2014-09-19
Start date
2015-08-01
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety stress

Interventions

None listed

Sponsors

Universiteit Leiden
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: (a) presence of anxiety disorder (b) age between 18 and 75 years

Exclusion criteria

Exclusion criteria: (a) depressieve stoornis (b) severe role impairments on various life domains (c) other severe psychiatric disorders

Design outcomes

Primary

MeasureTime frame
Behavioural measures: Affective states on the emotion regulation task and reaction times on working memory task. Imaging: Blood-Oxygen-Level Dependent (BOLD) response during the task; BOLD response during rest (functional connectivity); Diffusion tensor imaging (DTI) (structural connectivity).

Secondary

MeasureTime frame
Exploratory analyses will be done on functional and structural connectivity using fMRI during rest and DTI respectively. Moreover, eye-tracking will be used to measure participants* fixation patterns while watching the visual stimuli.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)