Cancer malignancy
Conditions
Interventions
None listed
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: bInclusion criteria cancer patients: 1. Patients with histological or cytological proof of metastatic cancer. 2. Age * 18 years 3. Able and willing to give written informed consent 4. Able and willing to undergo blood sampling ;Inclusion criteria healthy volunteers: 1. Age * 18 years 2. Able and willing to give written informed consent 3. Able and willing to undergo blood sampling
Exclusion criteria
Exclusion criteria: Exclusion criteria cancer patients: 1. Patients with known alcoholism, drug addiction, psychotic disorders in the history and/or other reasons, for which they are not amenable for adequate follow up. 2. Uncontrolled infectious disease or known HIV-1 or HIV-2 type patients ;Exclusion criteria healthy volunteers: 1. Patients with known alcoholism, drug addiction, psychotic disorders in the history and/or other reasons, for which they are not amenable for adequate follow up. 2. Uncontrolled infectious disease or known HIV-1 or HIV-2 type patients 3. Prior history of malignancy, renal disease, cardiovascular disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reproducible method for enumeration of CECs and CEPs in peripheral blood using FACS | — |
Secondary
| Measure | Time frame |
|---|---|
| Gain further insight in the origin of CECs and CEPs. | — |
Countries
Netherlands
Outcome results
None listed