Juvenile idiopathic arthritis juvenile rheumatoid arthritis
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Healthy controls will be matched to JIA patients based on age and sex. In order to be eligible to participate in this study, a patient must meet all of the following criteria: - From 6 to 17 years of age - Ability to speak Dutch -Be diagnosed with active JIA by their treating physician as defined by the ILAR-classification and patient reported pain rating greater than 10 (on a 0-100mm scale). - The most severe inflammation must be in the knee;Healthy controls must meet all of the following criteria: - From 6 to 17 years of age - Ability to speak Dutch
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: In the case of patients: - When there is any serious injury to the body regions to be tested - Severe comorbidity including but not limited to cystic fibrosis, cancer, inflammatory bowel disease; history of drug or alcohol abuse; severe psychiatric disorder or dysfunction (e.g., major depression or generalized anxiety disorder) - Inability to understand the instructions;In the case of healthy controls: - When there is any serious injury to the body regions to be tested - Health problems requiring medical treatment, history of drug or alcohol abuse; severe psychiatric disorder or dysfunction (e.g., major depression or generalized anxiety disorder) - Inability to understand the instructions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain sensitivity levels of the QST battery: Pain thresholds for temperature (hot,cold), pinprick, pressure, temporal summation of pinprick (*wind-up*), and allodynia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection sensitivity levels of the QST battery: temperature (warm, cold), mechanical, and vibration. | — |
Countries
Netherlands
Outcome results
None listed