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Comparison of flow-mediated dilatation with local thermal hyperaemia as a measure of endothelial function.

Comparison of flow-mediated dilatation with local thermal hyperaemia as a measure of endothelial function. - BeeJEM

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON40563
Enrollment
40
Registered
2014-06-05
Start date
2014-08-17
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bloedvataandoeningen

Interventions

Beetroot juice and placebo.

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Non-smokers: - Healthy Men - Age between 25-65 years - Non-smoking for > 5 years - Body mass index between 18 and 30 kg/m2 - Capable and willing to give informed consent - General good health, based on medical history and physical examination - Systolic BP measured on day of the experiment should be

Exclusion criteria

Exclusion criteria: - female subjects - History of cardiovascular disease - Use of vasoactive drugs - Drug or/and alcohol abuse

Design outcomes

Primary

MeasureTime frame
Degree of correlation between FMD and LTH

Secondary

MeasureTime frame
Involvement of NO in LTH response Changes in FMD and LTH in response to beetroot juice consumption

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)