The effect of High Pressure level determined by Electrical Impedance Tomography on hemodynamics during Airway Pressure Release Ventilation (APRV) in patients with severe ARDS: a pilot-study

The effect of High Pressure level determined by Electrical Impedance Tomography on hemodynamics during Airway Pressure Release Ventilation (APRV) in patients with severe ARDS: a pilot-study - EIT guided APRV settings in ARDS patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40559

Enrollment

Registered

2014-03-13

Start date

2014-01-01

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome ARDS

Interventions

After baseline measurement, ventilator mode is switched from CMV to APRV. Phigh levels are determined based on EIT measurements. The order of both APRV settings will be randomized.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: >18 years Written informed consent from legal representatives PaO2/FiO2 ratio

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean arterial blood pressure	—

Secondary

Measure	Time frame
Homogeneous ventilation (intratidal gas distribution) of the lungs as measured by EIT Blood gas exchange Respiratory parameters Cardiac Output (if available)	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)