Is Platelet Reactivity Measured with the VerifyNOw P2Y12 Platelet Function Assay Influenced by the Performance of a PCI Procedure and Procedural Characteristics - The POPular Process study

Is Platelet Reactivity Measured with the VerifyNOw P2Y12 Platelet Function Assay Influenced by the Performance of a PCI Procedure and Procedural Characteristics - The POPular Process study - POPular Process

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40557

Enrollment

115

Registered

2014-01-16

Start date

2014-01-28

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

angioplasty percutaneous coronary intervention

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Scheduled for PCI 2. Adequately treated with clopidogrel (for the definition of adequate treatment see protocol page 9)

Exclusion criteria

Exclusion criteria: 1. Unable or unwilling to give informed consent 2. Presentation with ST-segment elevated myocardial infarction (STEMI) 3. Thrombolytic therapy within 24 hours before PCI or GPIIb/IIIa-inhibitors within the last 14 days 4. Laboratory results or diseases leading to unreliable VerifyNow results such as a known platelet count

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the difference in mean PRU value before and after the procedure in the arterial blood samples in patients treated with clopidogrel.	—

Secondary

Measure	Time frame
Secondary endpoint is the difference in mean PRU value before and after the procedure in the venous blood samples. Secondary endpoint is the difference in mean PRU value between arterial and venous blood samples before and after the procedure. Secondary endpoint is the difference in the rate of HPR before and after the procedure in arterial blood samples and in venous blood samples. Secondary endpoint is the correlation between hematocrit and PRU values	—

Measure

Time frame

Secondary endpoint is the difference in mean PRU value before and after the procedure in the venous blood samples. Secondary endpoint is the difference in mean PRU value between arterial and venous blood samples before and after the procedure. Secondary endpoint is the difference in the rate of HPR before and after the procedure in arterial blood samples and in venous blood samples. Secondary endpoint is the correlation between hematocrit and PRU values

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Countries

Netherlands

Outcome results