Computer based cognitive flexibility training after stroke

Computer based cognitive flexibility training after stroke - TAPASS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40530

Enrollment

160

Registered

2013-07-09

Start date

2013-09-17

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular accident Stroke

Interventions

Participants will be randomized over three conditions: online cognitive flexibility training, online mock training (active control), or waiting list. The training duration is 12 weeks during which p

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Suffered from stroke and referred to rehabilitation; 2) Presence of cognitive dysfunction due to stroke; 3) Age between 30 and 80 years; 4) Daily access to computer with internet connection and able to use mouse; 5) lnformed consent for study participation.

Exclusion criteria

Exclusion criteria: 1) Any disease other than stroke which results in severe cognitive impairments 2) Severe psychological, psychiatric, or somatic comorbidity which could strongly influence the performance on the neuropsychological assessment and training possibilities 3) Mentally (Telephone Interview Cognitive Status (TICS) score

Design outcomes

Primary

Measure	Time frame
The primary outcome is executive functioning as measured by several neuropsychological tasks (Fluency, Tower of London, Trail Making Test, letter-number sequencing) See protocol for a description of these tasks.	—

Secondary

Measure	Time frame
1) Cognitive flexibility as measured by switchcost (reactietimes op switchtrials compared to reaction times on non -switchtrials) on the switch task. 2) Cognitive functioning as measured by several neuropsychological tasks and computer tasks (see protocol) 3) Training improvement 4) Subjective cognitive functioning and functioning in daily life as measured by: dysexecutive questionnaire (DEX), Cognitive Failure Questionnaire (CFQ), Utrechtse Schaal voor Evaluatie en Revalidatie- Participatie (USER-P), Instrumental activity of daily life scale (IADL), en Short Form Health Survey (SF-36) 5) Imaging analyses (resting state fMRI, Diffusion Tensor Imaging, Voxel Based Morphometry)	—

Measure

Time frame

1) Cognitive flexibility as measured by switchcost (reactietimes op switchtrials compared to reaction times on non -switchtrials) on the switch task. 2) Cognitive functioning as measured by several neuropsychological tasks and computer tasks (see protocol) 3) Training improvement 4) Subjective cognitive functioning and functioning in daily life as measured by: dysexecutive questionnaire (DEX), Cognitive Failure Questionnaire (CFQ), Utrechtse Schaal voor Evaluatie en Revalidatie- Participatie (USER-P), Instrumental activity of daily life scale (IADL), en Short Form Health Survey (SF-36) 5) Imaging analyses (resting state fMRI, Diffusion Tensor Imaging, Voxel Based Morphometry)

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)