Adrenaline use in local infiltration analgesia during TKA;Randomized, double blind, controlled study

Adrenaline use in local infiltration analgesia during TKA;Randomized, double blind, controlled study - LIA with or without adrenaline in TKA

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40518

Enrollment

Registered

2014-05-09

Start date

2014-06-01

Completion date

Unknown

Last updated

2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee wear osteoarthritis of the knee joint

Interventions

Local Infiltration analgesia with ropivacaine with or without adrenaline.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Painful and disabled knee joint resulting from osteoarthritis • High need to obtain pain relief and improve function • Able and willing to follow instructions • Informed consent

Exclusion criteria

Exclusion criteria: • Active infection in knee • General infection • Distant foci of infections which may spread to the implant site • Failure of previous joint replacement • Pregnancy

Design outcomes

Primary

Measure	Time frame
VAS-painscore, post operative pain relief - Direct after the operation - Before and after the first mobilisation - Pain measure 3 times a day on standard time 3 a day on fixed intervals until discharge	—

Secondary

Measure	Time frame
- Amount of post operative analgesia use direct post operative till day of discharge - Time to fisrt mobilisation - Length of hospital stay - Adverse events/complications: Intra-operative, post-operative during pilot study	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)