Bronchial asthma overweight
Conditions
Interventions
Pulmonary rehabilitation: during 12 weeks three times a week a training of 60
minutes under supervision of a physiotherapist, and with counselling of a
psychologist and a dietician. .
Laparoscopic
Sponsors
Sint Franciscus Gasthuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -Age > 18 and 0.75 despite optimized medication use (LABA and ICS) -BMI > 35 kg/m2 with a maximum weight of 150 kg -Ability to perform a reproducible lung function test -Ability to participate in pulmonary rehabilitation -Approval for 3 , 6 and 12 months follow-up visits, and patient motivation to achieve the fullest benefit from pulmonary rehabilitation. -Informed consent
Exclusion criteria
Exclusion criteria: -Significant orthopedic or neurologic problems that reduce mobility or cooperation with physical training. -COPD or other pulmonary pathology apart from asthma, except for adequate treated OSAS with a AHI 10 PY in history -Participation in Pulmonary Rehabilition program in last 2 year before the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are BMI, Asthma-related quality of life (AQLQ), activity level (move-monitor), lung function (FEV1), exercise capacity (6MWD), postoperative complications, cancelled surgeries, inflammation (blood). Tertiary endpoint are symptoms scores, patient utilities (EQ5D5L), postoperative complications, cancelled surgeries and the incremental cost-effectiveness of pulmonary rehabilitation + laparoscopic bariatric surgery as compared to laparoscopic bariatric surgery alone. | — |
Primary
| Measure | Time frame |
|---|---|
| Symptom scores (asthma control questionnaire (ACQ)), 3 months after bariatric surgery. | — |
Countries
Netherlands
Outcome results
None listed