Effect of sitting less on glucose regulation in people with diabetes mellitus type 2

Effect of sitting less on glucose regulation in people with diabetes mellitus type 2 - SIT LESS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40499

Enrollment

Registered

2013-12-30

Start date

2013-11-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes diabetes mellitus type 2

Interventions

Three activity regimes: sitting, exercise and non-sitting regime of each 4 days

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: o Men and women: 40-75 years old o Diabetes mellitus type 2, developed after the age of 40 years old o Treatment with diet or oral blood lowering medication and a Hba1C

Exclusion criteria

Exclusion criteria: o Pregnancy o Alcohol use: > 2 units per day (during the last 3 months) o Experimental drug use (during the last 3 months) o Use of insulin, corticosteroids, vitamin K antagonists and immunosuppresiva o Triglycerides > 10.0 mmol/l o Fasting glucose >= 11 mmol/l o Heart failure NYHA 3 or higher o COPD Gold 3 or higher o Glomerular filtration rate (GFR)

Design outcomes

Primary

Measure	Time frame
glucose regulation measured by continous glucose monitoring	—

Secondary

Measure	Time frame
- Fasting total cholesterol, non HDL cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, apo B, apo A, en free fatty acids - Fasting glucose, insulin and C-peptide - High sensitivity CRP, interleukin 1 and 6	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)