Behavioral and psychological characteristics of children with narcolepsy

Behavioral and psychological characteristics of children with narcolepsy - Behavioral and psychological characteristics of children with narcolepsy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40494

Enrollment

Registered

2014-03-12

Start date

2014-04-10

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Narcolepsy

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Narcolepsy: - Children with the diagnoses of narcolepsy according to the ICSD-2 criteria (both with and without cataplexy);- Due to age restrictions of the various instruments, children from 7 to 16 years old will be included in this study. For children who are diagnosed with narcolepsy during the course of the study and will participate as 'new diagnosis', an upper limit of 15 years has to be maintained. This is related to the age restriction of the WISC III NL;- Under treatment at one of the participating centers (ie Kempenhaeghe, UZ Gent, MC Haaglanden and LUMC);Juvenile idiopathic arthritis:;- Children with a diagnosis of juvenile idiopathic arthritis according to ILAR classification - Children between the ages of 7 to 16 years - At least one year under the supervision of a specialist - Minimal treatment with NSAIDs and MTX;Healthy controls:;- Children between the ages of 7 to 16 years - No medical diagnosis / treatment

Exclusion criteria

Exclusion criteria: For both clinical groups and healthy controls:;- - Intellectual disability of the child (IQ

Design outcomes

Primary

Measure	Time frame
Given the exploratory nature of the study, there are several primary study parameters. Regarding the personality there is particular interest in the dimensions: 'extraversion' and 'emotional stability'. These are obtained from the Hierarchical personality questionnaire for children (HIPIC) and the Dimensional Personality Symptom Item Pool (DiPSI) and serve as the primary study parameter for personality traits. Social behavior is measured by the subscale 'autistic behaviors' obtained from the Social Emotional Questionnaire (SEV). The overall IQ score obtained from the Wechsler Intelligence Scale (WISC-III-NL) is chosen as the primary parameter for intellectual functioning.	—

Measure

Time frame

Given the exploratory nature of the study, there are several primary study parameters. Regarding the personality there is particular interest in the dimensions: 'extraversion' and 'emotional stability'. These are obtained from the Hierarchical personality questionnaire for children (HIPIC) and the Dimensional Personality Symptom Item Pool (DiPSI) and serve as the primary study parameter for personality traits. Social behavior is measured by the subscale 'autistic behaviors' obtained from the Social Emotional Questionnaire (SEV). The overall IQ score obtained from the Wechsler Intelligence Scale (WISC-III-NL) is chosen as the primary parameter for intellectual functioning.

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Secondary

Measure	Time frame
Secondary outcome measures include 'internalizing' from the Child Behavior Checklist (CBCL) and the total score of the Child Depression Inventory (CDI).	—

Countries

Netherlands

Outcome results