Schizophrenia vulnerabilty for psychosis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Diagnosis of schizophrenia according to DSM-IV-TR (early onset en late onset) - Age between 18 and 65 years. Exclusion of patients older than 65 years considering the influence of aging processes on cognition.
Exclusion criteria
Exclusion criteria: - Substance dependence according to the DSM-IV-TR. - Personality in A or B cluster according to the DSM-IV-TR. - Moderate to severe depressive disorder according to the DSM-IV-TR. - Total IQ score below 70 on the Wechsler Adult Intelligence Scale IV (WAIS-IV). - Patient wholly or partially deaf or blind. - Patient doesn't suffiently understand explanations and instructions prior to the study or insufficient (eg insufficient mastery of Dutch). - Congenital and non-congenital hersenletslel. - Amnestic syndromes according to the DSM-IV-TR. - Suicidality - GAF
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary hypothesis The researchers will translate the IMI-SR into Dutch. Then a native speaker will translate it back into English, and both the back-translated English version of the IMI-SR and the original English version will be compared. Reliability and validity of the N-IMI-SR: Internal (item-)consistency, test-retest reliability, convergent and divergent validity. Convergent validity: Performance Motivation Test (PMT). Divergent validity: Symptom Checklist 90 Revised (SCL-90-R). Secondary hypothesis The correlation between motivation and cognition is determined Motivation measures - N-IMI-SR Cognition measures: - Wechsler Adult Intelligence Scale IV (WAIS-IV), measuring intelligence. - Winsconsin Card Sorting Test (WCST), measuring executive functioning, planning and organizing abilities. - Trail Making Test (TMT), measuring attention. | — |
Countries
Netherlands