joint inflammation
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -Adult (older than 18 years of age) -Diagnosed with rheumatoid arthritis or peripheral spondyloarthritis according to the treating rheumatologist. -Undergoing a diagnostic or therapeutic arthroscopy of the knee -Able to give a written informed consent after reading and understanding the letter of information.
Exclusion criteria
Exclusion criteria: -Patients who fail to meet the inclusion criteria. -Patients deemed unfit to participate in the study for whatever reason by the physician performing the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endpoints of the study are analysis of the immune cells in the synovial biopsies of 80 patients with knee arthritis, analysis of molecules involved in osteoblast and osteoclast activation and analysis of the effect of molecules in synovial fluid on activation of osteoclasts and osteoblasts in vitro. | — |
Countries
Netherlands
Outcome results
None listed