Advanced glycation end products (AGE) measured by skin autofluorescence and the association with vascular compliance in children with type 1 diabetes.

Advanced glycation end products (AGE) measured by skin autofluorescence and the association with vascular compliance in children with type 1 diabetes. - Skin AF en vascular compliance in DM1 children

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40440

Enrollment

280

Registered

2014-09-23

Start date

2014-09-24

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes Mellitus

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: type 1 diabetes

Exclusion criteria

Exclusion criteria: Other forms of diabetes (type 2, MODY, CFRD etc.) Local skin disease of the lower arm obviating skin autofluorescence measurement Very dark skin influencing skin autofluorescence measurement (reflectance

Design outcomes

Primary

Measure	Time frame
AGE-measurement, vascular compliance and endothelial markers in blood.	—

Secondary

Measure	Time frame
Duration of diabetes, HbA1c, BMI, body composition, smoking, lipid concentrations, microalbuminuria, retinopathy, insulin dosage per kg body weight, family history of cardiovascular disease, hypertension, hypercholesterolemie or diabetes.	—

Countries

Netherlands

Outcome results