Microcirculatory and macrocirculatory alterations in different thyroid states

Microcirculatory and macrocirculatory alterations in different thyroid states - Microcirculation in different thyroid states

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40419

Enrollment

Registered

2014-11-24

Start date

2014-09-01

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac function microvasculature

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with differentiated thyroid carcinoma who have to receive a treatment with radioactive iodine. Has the capacity to understand and willingness to sign an informed consent form Aged 18-80 years

Exclusion criteria

Exclusion criteria: * Other malignancy * Clinically relevant active systemic disease (such as autoimmune or infectious diseases) * Pregnancy * Heart failure (New York Heart Association (NYHA) classes II, III or IV)

Design outcomes

Primary

Measure	Time frame
changes in cardiac function (cardiac output and mean arterial bloodpressure) and microcirculatory function (as measured with Cytocam) in different thyroid states.	—

Secondary

Measure	Time frame
• Capillary refill time • Skin-difference temperature gradient (Tskin-diff) • Peripheral perfusion index (PI) • Transthoracic cardiac ultrasound • Heart rate	—

Countries

Netherlands

Outcome results