chronic sleep deprivation/social jetlag daytime deprivation
Conditions
Interventions
For 16 consecutive days from 8 hours before mid-sleep (MSFsc, chronotype, as
assessed by the Munich Chronotype Questionnaire before the study) until actual
sleep time (lights out) participants will
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy men and women between 18 and 45 years of age Social jetlag = difference between mid-sleep on workdays and days off of minimum 2 hours Written informed consent*
Exclusion criteria
Exclusion criteria: Sleep disorders, e.g. sleep apnoea, narcolepsy, restless legs, primary insomnia (will be asked in the General Questionnaire, appendix F1a) Mood disorder; because of the possibility of depressive mood as co morbidity in late chronotypes we will set the criterion for exclusion based on depressive mood on a BDI-II (appendix F1h) rating equal to or higher than 16 (indicating severe dysphoric or depressed mood) Two or more time zones crossed 1 month before study participation Shift-work during 5 years prior to participation Recent eye surgery (last year), glaucoma or other eye disease History of chronic diseases, and/or use of chronic medication for 3 months or longer before study participation Alcohol or drug problems (based on answers to the General Questionnaire, appendix F1a) The use of sleep and photosensitizing medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep timing and sleep quantity from sleep diaries (subjective) and actimetry (objective) | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality from subjective sleep diaries, rest-activity profiles from objective actimetry, light exposure from sleep diaries (subjective) and from actimetry (objective). In addition, secondary parameter in this study is the rhythm of melatonin concentration in saliva. The start of the rhythm will be measured: dim light melatonin onset (DLMO). A shift in DLMO is interpreted as a shift in the endogenous circadian pacemaker. | — |
Countries
Netherlands
Outcome results
None listed