The study is not primarily aimed at a disease but normal neural and cognitive function. It is secondarily related to anxiety and aggression. Anxiety fearjavascript:saveABR('C')
Conditions
Interventions
None listed
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy, adult subjects aged 18 to 34.
Exclusion criteria
Exclusion criteria: - Abnormal hearing or (uncorrected) vision. - Average use of more than 3 alcoholic beverages daily. - Average use of psychotropic medication or recreational drugs weekly or more. - Inability or significant difficulty to cease smoking for 24 hours prior to testing. - Use of psychotropic medication, or of recreational drugs over a period of 72 hours prior to each test session, and use of alcohol within the last 24 hours before each measurement. - Metal objects in or around the body (braces, pacemaker, metal fragments, hearing devices). - Prior or current psychiatric or neurological treatment or current psychiatric treatment. - History of autonomic failure (e.g., vasovagal reflex syncope). - Claustrophobia. - Intense daily physical exercise. - History of cardiovascular disease. - Current stressful episode or major life event
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study measurement is the contrast between BOLD responses for the various task conditions. We will also measure effective connectivity in brain activity, heart rate, heart rate variability, pupil dilation, and behaviour (body sway, reaction time and accuracy) during the different conditions of the task. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
Netherlands
Outcome results
None listed