PSYchological factors and Cardiovascular, Hormonal and Emotional responses to stress in patients with established coronary artery disease (PSYCHE)

PSYchological factors and Cardiovascular, Hormonal and Emotional responses to stress in patients with established coronary artery disease (PSYCHE) - PSYCHE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40395

Enrollment

200

Registered

2013-10-28

Start date

2013-12-12

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute coronary syndrome atherosclerosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Elective percutaneous coronary intervention 3-4 months ago, stable, without complaints related to this PCI, or acute percutaneous coronary intervention 6 months ago, stable, without complaints related to this PCI;Not on beta-blocker medication or willing to discontinue beta-blocker medication for 48 hours preceding the stress test (when agreed upon by treating intervention cardiologist);Aged >=18;Fluent in Dutch

Exclusion criteria

Exclusion criteria: Life threatening comorbidity (e.g. cancer) or psychiatric disorder (except mood disorders) Unstable at 3 months post-elective PCI, with complaints, or unstable at 6 months post- acute PCI, with complaints.

Design outcomes

Primary

Measure	Time frame
Predictors: Psychological risk factors (depression, anxiety, Type D personality, mindfulness); Outcome variables: hormonal (cortisol), hemodynamic (blood pressure, cardiac output), and myocardial (pre-ejection period, heart rate variability, heart rate) stress reactivity.	—

Secondary

Measure	Time frame
complications, events and death at 1 year after PCI	—

Countries

Netherlands

Outcome results