The role of neutrophil extracellular trap formation in sickle cell disease

The role of neutrophil extracellular trap formation in sickle cell disease - NET, in-vitro experiments

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40345

Enrollment

Registered

2014-03-12

Start date

2015-01-30

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sickle cell

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: For patients: 1. High performance liquid chromatography confirmed diagnosis of HbSS, HbSC, HbS*0- or HbS*+-thalassemia genotype in SCD patients. 2. Written informed consent by the patient. 3.18 years and older For healthy volunteers: 1. Age * 18 years; 2. WHO performance score 0; 3. healthy race-matched family member or acquaintance

Exclusion criteria

Exclusion criteria: For patients 1. HbSC or HbS*+- thalassemia genotype . 2. Pregnancy 3. Active cancer 4. Chronic HIV infection 5. Recent vaso-occlusive crisis (

Design outcomes

Primary

Measure	Time frame
n.a.	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results