The identification of genetic variants in pedigrees with a high genetic loading for alcohol dependence

The identification of genetic variants in pedigrees with a high genetic loading for alcohol dependence - Genetics_alcohol

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40342

Enrollment

280

Registered

2013-11-14

Start date

2014-02-14

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction alcohol dependence

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have given informed consent to participate and who at the screening visit have met all the below stated inclusion criteria.;Diagnosed with alcohol dependence according to DSM-IV criteria Age between 16-85 years Caucasian ethnicity (i.e., defined as having at least three Caucasian grandparents) A positive family history of alcohol dependence;2. Relatives who have given informed consent to participate and who at the screening visit have met all the below stated inclusion criteria.;Age between 16-85 years Caucasian ethnicity (at least three Caucasian grandparents)

Exclusion criteria

Exclusion criteria: Age below 16 Non-caucasian

Design outcomes

Primary

Measure	Time frame
Addiction severity index (ASI), including demographic data Alcohol use disorders identification test (AUDIT) Cannabis use disorders identification test (CUDIT and additional items CUDIT-Revised) Fagerström test for Nicotine Dependence (FTND) Gambling section of the EuropASI versie III (see ASI) Compulsive Internet Use Scale (CIUS) Eating Disorder Examination Questionnaire (EDE-Q) Ethnicity Mini-plus (modules A-P) Adult ADHD Self-Report Scale (ASRS) Hospital Anxiety and depression scale (HADS) Family Interview for Genetic Studies (FIGS)	—

Measure

Time frame

Addiction severity index (ASI), including demographic data Alcohol use disorders identification test (AUDIT) Cannabis use disorders identification test (CUDIT and additional items CUDIT-Revised) Fagerström test for Nicotine Dependence (FTND) Gambling section of the EuropASI versie III (see ASI) Compulsive Internet Use Scale (CIUS) Eating Disorder Examination Questionnaire (EDE-Q) Ethnicity Mini-plus (modules A-P) Adult ADHD Self-Report Scale (ASRS) Hospital Anxiety and depression scale (HADS) Family Interview for Genetic Studies (FIGS)

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Countries

Netherlands

Outcome results