Pain Postextraction Pain
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy subjects with age between 18 and 45 and BMI between 20 and 27 kg/m2 at screening
Exclusion criteria
Exclusion criteria: Clinically significant acute illness within 7 days prior to study procedure. Anti blood clotting medication Donation of 1 or more units (approximately 450 mL) of blood or acute loss of an equivalent amount of blood within 90 days prior to study procedure. Has received an experimental drug or used an experimental medical device within 30 days before the planned start of treatment. Allergy to standard rescue medication Ibuprofen. History of gastro-intestinal disturbances (gastropathy) Psychological and/or emotional problems, which would render the informed consent invalid, or limit the ability of the subject to comply with the study requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interpatient pain response on NRS, biomarkers and genetic profile. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed