Atrium fibrillation heart rhythm disturbance
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Any patient with an indication for catheter ablation treatment of symptomatic paroxysmal AF can enter the study.;The patients should conform to the following criteria: • Age between 18 and 80 years • Paroxysmal AF, as defined following the ESC 2010 Guidelines. • At least one class I or III anti-arrhythmic drug in standard dosage has failed or is not tolerated. • Legally competent and willing to sing the informed consent. • Willing and able to adhere to the follow up visit protocol.
Exclusion criteria
Exclusion criteria: If any of the following criteria is present, patients cannot enter the study and will thus not be asked for written informed consent: • Prior intervention (catheter ablation or minimally-invasive surgical ablation) for AF. • AF secondary to electrolyte imbalance, thyroid disease or other reversible or non-cardiovascular causes. • Active infection or sepsis (as evidenced by increased white blood cell count, elevated CRP level or fever >38,5C) • NYHA class IV heart failure symptoms or left ventricular ejection fraction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AF burden and the possibility of arrhythmia identification (AF, atrial flutter, atrial tachycardia) will be determined. Monitoring duration and patient compliance will be documented from the duration of the recordings and patient satisfaction will be measured using a questionnaire after the three week monitoring period. Finally, the changes in biomarkers involved in the reverse remodeling of the atrium in AF will be related to the burden of AF in the preceding monitoring periods. | — |
Countries
Netherlands
Outcome results
None listed