Pre-operative treatment with Erythropoietin and iron supplement for prevention of perioperative blood transfusion in cardiac surgery

Pre-operative treatment with Erythropoietin and iron supplement for prevention of perioperative blood transfusion in cardiac surgery - EPICS study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON40254

Enrollment

100

Registered

2014-01-13

Start date

2014-12-11

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bloodloss in cardiac surgery

Interventions

Group 1: pre-treated group: patients receive up to two boluses of erythropoietin subcutaneously and one bolus of iron supplement intravenously administered at the outpatient clinic by a special trai

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age of 18 years or more undergoing isolated CABG or AVR 2. Preoperative Hb

Exclusion criteria

Exclusion criteria: 1. Off pump surgery. 2. Combination surgery. 3. Re-operation. 4. Emergency operation. 5. Patients with bleeding disturbances;e.g, hemophilia and patients with chronic liver disease. 6. Concomitant use of cyclosporine prior to, during or following surgery 7. Female patients who are pregnant or planning to become pregnant.

Design outcomes

Primary

Measure	Time frame
The number of patients who receive RBC transfusion perioperatively.	—

Secondary

Measure	Time frame
The mean number of RBC units received per patient in the perioperative period.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)