Obesitas Asthmatic bronchitis overweight
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -Age > 18 and 30 ,and = 0.75 despite optimized medication use (LABA and ICS) -Ability to perform a reproducible lung function test -Ability to use the internet-based self management tool -Ability to participate in pulmonary rehabilitation -Consent to 3, 6 and 12 months follow-up visits. -Patient motivation to achieve the fullest benefit from pulmonary rehabilitation. -Informed consent
Exclusion criteria
Exclusion criteria: -Significant orthopaedic or neurologic problems that reduce mobility or cooperation with physical training -COPD or other pulmonary pathology apart from asthma, except for adequate treated OSAS with a AHI 10 PY in history -Participation in Pulmonary rehabilitation program in last 2 year before the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma symptom score (asthma control questionnaire (ACQ) score) 3 months after pulmonary rehabilitation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints will be BMI, asthma quality of life (AQLQ), activity level (move-monitor), exercise capacity (6MWD), lung function (FEV1) and airway inflammation (eosinophils and neutrophils in blood and sputum). Tertiary endpoints will be symptom scores, patient utilities (EQ5D5L), self-management characteristics(HeiQ) and exacerbation frequency. | — |
Countries
Netherlands