Adaptive Cognition in Autism

Adaptive Cognition in Autism - Adaptive Cognition

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40204

Enrollment

120

Registered

2013-12-12

Start date

2014-01-10

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Autism Spectrum Disorders

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age: 12 to 25 years old Intelligence: total IQ higher than 80 Participants with autism Typically developing control participants Participants with dyslexia

Exclusion criteria

Exclusion criteria: Motor impairments in the upper limbs (keyboard is used for the behavioural task); Metal in the body (due to the MRI); History of epilepsy (due to the EEG); Typically developing control participants should have no records of neurological or developmental disorders;

Design outcomes

Primary

Measure	Time frame
1. Task choice and task execution as behavioural measures, registered during the computer task; the former used to determine behavioural rigidity as the tendency to repeat tasks (repetition bias) and the latter to determine performance deterioration after a task switch (switch costs). 2. Task preparation (intentions) and task execution (actions): slow frontal negativity (contigent negative variation) and positive more parietal component (P3), respectively, as their main EEG markers. 3. Size, shape, and patterns of brain activation (with a specific focus on orbitofrontal areas) measured by (f)MRI.	—

Measure

Time frame

1. Task choice and task execution as behavioural measures, registered during the computer task; the former used to determine behavioural rigidity as the tendency to repeat tasks (repetition bias) and the latter to determine performance deterioration after a task switch (switch costs). 2. Task preparation (intentions) and task execution (actions): slow frontal negativity (contigent negative variation) and positive more parietal component (P3), respectively, as their main EEG markers. 3. Size, shape, and patterns of brain activation (with a specific focus on orbitofrontal areas) measured by (f)MRI.

—

Secondary

Measure	Time frame
Reading ability, handedness, IQ, age, and gender will be taken as covariates.	—

Countries

Netherlands

Outcome results