the neuropsychiatric and personality profile of MS patients: its determinants and impact on daily life functioning. An extension of the FuProMS Study

the neuropsychiatric and personality profile of MS patients: its determinants and impact on daily life functioning. An extension of the FuProMS Study - NEUROPSYCHIATRIC CHANGES AND DAILY LIFE FUNCTIONING IN MS PATIENTS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40157

Enrollment

333

Registered

2014-05-01

Start date

2014-08-05

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS multiple sclerosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: definite diagnosis of MS, recruited between 1998-2000, participants in the FuProMS study at the last wave Controls: people aged 30 to 70 years, same catchment area as the patient base.

Exclusion criteria

Exclusion criteria: Patients: no exclusion criteria Controls: neurological disorder affecting the CNS.

Design outcomes

Primary

Measure	Time frame
(1) difference in frequency of self-reported neuropsychiatric symptoms / disorders and personality characteristics between patients and controls using the following questionnaires: CES-D, HADS, CNS-LS, PDI-21, MDQ-NL and EPQ-RSS (2) determinants of neuropsychiatric symptoms / disorders: biological markers (MRI parameters, family history), disease-related (including EDSS, fatigue, cognitive functioning and iatrogenic) and individual and psychosocial factors (demographic, locus of control, coping style, social support and premorbid personality ) (3) the impact of neuropsychiatric symptoms / disorders on daily life functioning measured by the FIM and SF-36	—

Measure

Time frame

(1) difference in frequency of self-reported neuropsychiatric symptoms / disorders and personality characteristics between patients and controls using the following questionnaires: CES-D, HADS, CNS-LS, PDI-21, MDQ-NL and EPQ-RSS (2) determinants of neuropsychiatric symptoms / disorders: biological markers (MRI parameters, family history), disease-related (including EDSS, fatigue, cognitive functioning and iatrogenic) and individual and psychosocial factors (demographic, locus of control, coping style, social support and premorbid personality ) (3) the impact of neuropsychiatric symptoms / disorders on daily life functioning measured by the FIM and SF-36

—

Countries

Netherlands

Outcome results