Late neonatal neurological outcome in infants with prenatally diagnosed duct dependent CHD and its relation with fetal and neonatal cerebral perfusion

Late neonatal neurological outcome in infants with prenatally diagnosed duct dependent CHD and its relation with fetal and neonatal cerebral perfusion - Perinatal cerebral perfusion in congenital heart disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON40142

Enrollment

Registered

2014-04-25

Start date

2014-04-30

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart defect heart disease

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Mothers of fetusses suspected of CHD and their subsequent newborn infant with duct dependent congenital heart defect Gestational age > 35 weeks

Exclusion criteria

Exclusion criteria: Large congenital cerebral malformation Severe chromosomal defect

Design outcomes

Primary

Measure	Time frame
Qualitative assessment of GMs according to Prechtl*s method. In addition, we will obtain motor optimality scores for more detailed analysis of the GMs;	—

Secondary

Measure	Time frame
Near-infrared Spectroscopy: cerebral (rcSO2) and systemic (rrSO2) oxygen saturation and FTOE; Pulsatility index (PI) and if possible maximum velocity of various arterial vessels, measured with Doppler ultrasound.	—

Countries

Netherlands

Outcome results